cytosol
Also known as cytoplasmic matrix, GO:0005829, intracellular fluid, groundplasm, ICF
thumb|right|300px|The cytosol is a crowded solution of many different types of molecules that occupy up to 30% of the cytoplasmic volume.
AI overview
The cytosol is the clear, liquid part inside cells that contains dissolved molecules and fills up to 30% of the space in the cytoplasm. It matters because many essential cellular activities happen in this crowded molecular environment, making it crucial for how cells function.
AI-generated from the Wikipedia summary — may contain errors.
Research
152,407 papers- [Cytosol malate dehydrogenase in Calicophoron ijimai trematodes and the effect of antiparasitic preparations on its activity].ReviewParazitologiia · 1983Vykhrestiuk NP, Khamatova AIu
- Cytosolic and endoplasmic reticulum chaperones inhibit wt-p53 to increase cancer cells' survival by refluxing ER-proteins to the cytosol.eLife · 2025Dabsan S, Zur G, Abu-Freha N et al.DOI: 10.7554/eLife.102658
- Cytosolic RNA binding of the mitochondrial TCA cycle enzyme malate dehydrogenase.RNA (New York, N.Y.) · 2024Noble M, Chatterjee A, Sekaran T et al.DOI: 10.1261/rna.079925.123
- In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species.Xenobiotica; the fate of foreign compounds in biological systems · 2020Juvonen RO, Pentikäinen O, Huuskonen J et al.DOI: 10.1080/00498254.2020.1711544
~16 min read
Article
14 sectionsContents
- Definition
- Properties and composition
- Water
- Ions
- Macromolecules
- Organization
- Concentration gradients
- Protein complexes
- Protein compartments
- Biomolecular condensates
- Cytoskeletal sieving
- Function
- References
- Further reading
thumb|right|300px|The cytosol is a crowded solution of many different types of molecules that occupy up to 30% of the cytoplasmic volume.
The cytosol, also known as cytoplasmic matrix or groundplasm, is one of the liquids found inside cells (intracellular fluid (ICF)). It is separated into compartments by membranes. For example, the mitochondrial matrix separates the mitochondrion into many compartments.