HPGDS
Sign in to saveAlso known as GSTS, GSTS1-1, PGD2, PGDS, GSTS1, hematopoietic prostaglandin D synthase
(Hematopoietic) PGDS protein, also known as Glutathione-Dependent PGD Synthase, is a protein that in humans is encoded by the HPGDS gene.
In the Vinony graph
Vinony's link graph records 5 inbound references to HPGDS, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Vinony links it to 6 Wikipedia language editions.
Gene data
HPGDS- Name
- hematopoietic prostaglandin D synthase
- Type
- protein-coding
- Position
- 94,298,507–94,342,876 (−)
- Aliases
- GSTS, GSTS1, GSTS1-1, PGD2, PGDS
- Ensembl
- ENSG00000163106
- RefSeq RNA
- NM_014485.3, XM_005262932.4, XM_054349696.1
- RefSeq protein
- NP_055300.1, XP_005262989.1, XP_054205671.1
Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
hematopoietic prostaglandin D synthase
- Symbol
- HPGDS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:94,298,507-94,342,876
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PGDS PDB 1iyh.png
Show 7 more facts
- HomoloGene ID
- 113741
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/27306
- genomic end
- 95264027
- genomic start
- 95219686
- chromosome
- human chromosome 4
- cytogenetic location
- 4q22.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
(Hematopoietic) PGDS protein, also known as Glutathione-Dependent PGD Synthase, is a protein that in humans is encoded by the HPGDS gene.
Gluthionine-dependent Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. As a type of Prostaglandin-D synthase, it catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.
Excerpted from Wikipedia’s “HPGDS” article, available under the CC BY-SA 4.0 licence.