glucuronosyltransferase
Sign in to saveAlso known as GT, UDP glucuronic acid transferase, uridine diphosphoglucuronyltransferase, UDP glucuronosyltransferase, UDPGA-glucuronyltransferase, uridine diphosphoglucuronosyltransferase, UDP glucuronyltransferase, UDP-glucuronyltransferase
'''Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UDPGT or UGT''') is a microsomal glycosyltransferase () that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. This is a glucuronidation reaction.
Key facts
- Enzyme.Name
- Glucuronosyltransferase
- Enzyme.EC_number
- 2.4.1.17
- Enzyme.CAS_number
- 9030-08-4
- Enzyme.GO_code
- 0015020
- Enzyme.image
- 2q6v.jpg
- Enzyme.width
- 270
- Enzyme.caption
- Glucuronosyltransferase monomer, Xanthomonas campestris
- Protein family.Symbol
- UDPGT
- Protein family.Name
- UDP-glucuronosyl and UDP-glucosyl transferase
- Protein family.image
- PDB 1rrv EBI.jpg
- Protein family.caption
- Structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.
- Protein family.Pfam
- PF00201
- Protein family.InterPro
- IPR002213
- Protein family.PROSITE
- PDOC00359
- Protein family.SCOP
- 1rrv
- Protein family.Membranome family
- 476
via Wikipedia infobox
Research
10,533 papers- [UDP-glucuronosyltransferase].Nihon eiseigaku zasshi. Japanese journal of hygiene · 2002
- UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects.Methods in enzymology · 2005
- Development and Evaluation of Ontogeny Functions of the Major UDP-Glucuronosyltransferase Enzymes to Underwrite Physiologically Based Pharmacokinetic Modeling in Pediatric Populations.Journal of clinical pharmacology · 2024
- UDP-glucuronosyltransferases.Current drug metabolism · 2000
- Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.Trends in endocrinology and metabolism: TEM · 2003
via PubMed
Wikidata facts
- Image
- PDB 1rrv EBI.jpg
Show 1 more fact
- EC enzyme number
- 2.4.1.17
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Function
- Diseases
- Causes
- Genes
- References
- External links
'''Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UDPGT or UGT') is a microsomal glycosyltransferase () that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. This is a glucuronidation reaction.
Alternative names:'' glucuronyltransferase UDP-glucuronyl transferase UDP-GT
Excerpted from Wikipedia’s “glucuronosyltransferase” article, available under the CC BY-SA 4.0 licence.