FUT9
Sign in to saveAlso known as Fuc-TIX, fucosyltransferase 9
Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT9 gene.
Gene data
FUT9- Name
- fucosyltransferase 9
- Type
- protein-coding
- Aliases
- Fuc-TIX
The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. [provided by RefSeq, Nov 2011].
via MyGene.info
Gene · Ensembl
fucosyltransferase 9
- Symbol
- FUT9
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:96,015,436-96,215,612
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 4800
- exact match
- identifiers.org/ncbigene/10690
- genomic start
- 96015974
- genomic end
- 96663488
- cytogenetic location
- 6q16.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT9 gene.
FUT9 is one of several alpha-3-fucosyltransferases that can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. FUT9 synthesizes the LeX oligosaccharide (CD15), which is expressed in organ buds progressing in mesenchyma during human embryogenesis.[supplied by OMIM]