FUT1
Sign in to saveAlso known as HH, HSC, fucosyltransferase 1 (H blood group), H
Galactoside 2-alpha-L-fucosyltransferase 1 is an enzyme that in humans is encoded by the FUT1 gene.
Gene data
FUT1- Name
- fucosyltransferase 1 (H blood group)
- Type
- protein-coding
- Position
- 48,748,011–48,755,390 (−)
- Aliases
- H, HH, HSC
- Ensembl
- ENSG00000174951
- RefSeq RNA
- NM_000148.4, NM_001329877.1, NM_001384359.1
- RefSeq protein
- NP_000139.1, NP_001316806.1, NP_001371288.1
This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq, Aug 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
fucosyltransferase 1 (H blood group)
- Symbol
- FUT1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:48,748,011-48,755,390
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 120
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2523
- genomic end
- 49258647
- genomic start
- 49251268
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.33
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Galactoside 2-alpha-L-fucosyltransferase 1 is an enzyme that in humans is encoded by the FUT1 gene.
The enzyme is involved in the synthesis of the H antigen.
Excerpted from Wikipedia’s “FUT1” article, available under the CC BY-SA 4.0 licence.