B3GAT2
Sign in to saveAlso known as GLCATS, beta-1,3-glucuronyltransferase 2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 is an enzyme that in humans is encoded by the B3GAT2 gene.
In the Vinony graph
Vinony's link graph records 407 inbound references to B3GAT2, and connects out to glucuronosyltransferase, PubMed and human chromosome 6.
It is catalogued under the topic Genes on human chromosome 6.
Vinony links it to 5 Wikipedia language editions.
Gene data
B3GAT2- Name
- beta-1,3-glucuronyltransferase 2
- Type
- protein-coding
- Position
- 70,856,679–70,957,464 (−)
- Aliases
- GLCATS
- Ensembl
- ENSG00000112309
- RefSeq RNA
- NM_080742.3, XM_047418209.1, XM_054354301.1
- RefSeq protein
- NP_542780.1, XP_047274165.1, XP_054210276.1
The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
beta-1,3-glucuronyltransferase 2
- Symbol
- B3GAT2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:70,856,679-70,957,464
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein B3GAT2 PDB 2d0j.png
Show 9 more facts
- HomoloGene ID
- 50574
- genomic end
- 71666741
- genetic association
- obesity
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/135152
- genomic start
- 71566382
- chromosome
- human chromosome 6
- cytogenetic location
- 6q13
- expressed in
- corpus callosum
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Use of HNK-1 Antibody for Neural Crest Research
- References
- External links
- Further reading
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 is an enzyme that in humans is encoded by the B3GAT2 gene.
The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system.
Excerpted from Wikipedia’s “B3GAT2” article, available under the CC BY-SA 4.0 licence.