B3GAT2
Sign in to saveAlso known as GLCATS, beta-1,3-glucuronyltransferase 2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 is an enzyme that in humans is encoded by the B3GAT2 gene.
Gene data
B3GAT2- Name
- beta-1,3-glucuronyltransferase 2
- Type
- protein-coding
- Position
- 70,856,679–70,957,464 (−)
- Aliases
- GLCATS
- Ensembl
- ENSG00000112309
- RefSeq RNA
- NM_080742.3, XM_047418209.1, XM_054354301.1
- RefSeq protein
- NP_542780.1, XP_047274165.1, XP_054210276.1
The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
beta-1,3-glucuronyltransferase 2
- Symbol
- B3GAT2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:70,856,679-70,957,464
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Use of HNK-1 Antibody for Neural Crest Research
- References
- External links
- Further reading
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 is an enzyme that in humans is encoded by the B3GAT2 gene.
The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system.
Excerpted from Wikipedia’s “B3GAT2” article, available under the CC BY-SA 4.0 licence.