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GeneQ18046363· pop 5· linked from 83 articles

Also known as BLOC2S3, HPS6, biogenesis of lysosomal organelles complex 2 subunit 3, HPS6 biogenesis of lysosomal organelles complex 2 subunit 3

Hermansky–Pudlak syndrome 6 (HPS6), also known as ruby-eye protein homolog (Ru), is a protein that in humans is encoded by the HPS6 gene.

Gene data

HPS6
Name
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
Type
protein-coding
Position
102,065,349–102,068,036 (+)
Aliases
BLOC2S3
RefSeq RNA
NM_024747.6
RefSeq protein
NP_079023.2

This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 5 protein. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 6. [provided by RefSeq, Jul 2008].

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HPS6 biogenesis of lysosomal organelles complex 2 subunit 3

Symbol
HPS6
Biotype
Protein coding
Organism
Homo sapiens
Location
10:102,065,349-102,068,036
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

5 sections
Contents
  • Function
  • Clinical significance
  • References
  • Further reading
  • External links

Hermansky–Pudlak syndrome 6 (HPS6), also known as ruby-eye protein homolog (Ru), is a protein that in humans is encoded by the HPS6 gene.

== Function == This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. HPS6 along with HPS3 and HPS5 form a stable protein complex named Biogenesis of Lysosome-related Organelles Complex-2 (BLOC-2).

Excerpted from Wikipedia’s “HPS6” article, available under the CC BY-SA 4.0 licence.

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