hydrogenase
Sign in to saveA hydrogenase is an enzyme that catalyses the reversible oxidation of molecular hydrogen (H2), as shown below:
Research
6,074 papers- Heterologous Hydrogenase Overproduction Systems for Biotechnology-An Overview.International journal of molecular sciences · 2020
- Studies on hydrogenase.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2013
- Biosynthesis and assembly of hydrogenase [NiFe]-cofactor: recent advances and perspectives.Metallomics : integrated biometal science · 2025
- Structural Insight into [NiFe] Hydrogenase Maturation by Transient Complexes between Hyp Proteins.Accounts of chemical research · 2020
- [NiFeSe]-hydrogenase chemistry.Accounts of chemical research · 2015
via PubMed
Wikidata facts
Show 1 more fact
- EC enzyme number
- 1.12.-.-
Sources (2)
via Wikidata · CC0
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Article
14 sectionsContents
- Structural classification
- [NiFe] hydrogenase
- [FeFe] hydrogenase
- [Fe]-only hydrogenase
- Mechanism
- Biological function
- Applications
- Biological hydrogen production
- Hydrogenase-based biofuel cells
- Principle
- Advantages
- Biochemical classification
- References
- External links
A hydrogenase is an enzyme that catalyses the reversible oxidation of molecular hydrogen (H2), as shown below:
Hydrogen oxidation () is coupled to the reduction of electron acceptors such as oxygen, nitrate, ferric ion, sulfate, carbon dioxide (), and fumarate. On the other hand, proton reduction () is coupled to the oxidation of electron donors such as ferredoxin (FNR), and serves to dispose excess electrons in cells (essential in pyruvate fermentation). Both low-molecular weight compounds and proteins such as FNRs, cytochrome c3, and cytochrome c6 can act as physiological electron donors or acceptors for hydrogenases.