hydrolase

Also known as EC 3, hydrolytic enzyme, hydrolases

In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond:

Research

1,654,217 papers

The SGNH hydrolase family: a template for carbohydrate diversity.Glycobiology · 2022
Emerging Strategies in Polyethylene Terephthalate Hydrolase Research for Biorecycling.ChemSusChem · 2021
Alpha/beta hydrolase fold: an update.Protein and peptide letters · 2009
Alpha/Beta-hydrolase fold enzymes: structures, functions and mechanisms.Current protein & peptide science · 2000
Peptide-Based Catalyst Mimicking Hydrolase Enzyme.Journal of peptide science : an official publication of the European Peptide Society · 2025

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Wikidata facts

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Commons category: Hydrolases
EC enzyme number: 3.-.-.-

Sources (3)

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Article

7 sections

Contents

Nomenclature
Classification
Clinical considerations
Membrane-associated hydrolases
Etymology and pronunciation
See also
References

In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond: \ce{A-B + H2O} \quad \xrightarrow[\text{ hydrolase }]{} \quad \ce{A-OH + B-H}

This typically results in dividing a larger molecule into smaller molecules. Some common examples of hydrolase enzymes are esterases including lipases, phosphatases, glycosidases, peptidases, and nucleosidases.