RAB23
Sign in to saveAlso known as HSPC137, RAB23, member RAS oncogene family
Ras-related protein Rab-23 is a protein that in humans is encoded by the RAB23 gene. Alternative splicing occurs at this gene locus and two transcript variants encoding the same protein have been identified.
Gene data
RAB23- Name
- RAB23, member RAS oncogene family
- Type
- protein-coding
- Position
- 57,186,992–57,222,848 (−)
- Aliases
- CRPT1, HSPC137
- Ensembl
- ENSG00000112210
- RefSeq RNA
- NM_001278666.2, NM_001278667.2, NM_001278668.2, NM_016277.5, NM_183227.3
- RefSeq protein
- NP_001265595.1, NP_001265596.1, NP_001265597.1, NP_057361.3, NP_899050.1
This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RAB23, member RAS oncogene family
- Symbol
- RAB23
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:57,186,103-57,222,848
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein RAB23 PDB 1z22.png
Show 5 more facts
- HomoloGene ID
- 7503
- exact match
- identifiers.org/ncbigene/51715
- genomic end
- 57222307
- genomic start
- 57053607
- cytogenetic location
- 6p12.1-p11.2
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Ras-related protein Rab-23 is a protein that in humans is encoded by the RAB23 gene. Alternative splicing occurs at this gene locus and two transcript variants encoding the same protein have been identified.
== Function ==