hyperprolactinemia
Sign in to saveAlso known as Chiari-Frommel syndrome, Pregnancy-related A-G syndrome (disorder), hyperprolactinaemia, Pregnancy-related A-G syndrome, hereditary hyperprolactinemia (disease), Familial isolated prolactin receptor deficiency, HYPERPROLACTINEMIA; HPRL
Hyperprolactinaemia (also spelled hyperprolactinemia) is a condition characterized by abnormally high levels of prolactin in the blood. In women, normal prolactin levels average to about 13 ng/mL, while in men, they average 5 ng/mL. The upper normal limit of serum prolactin is typically between 15 and 25 ng/mL for both men and women. Levels exceeding this range indicate hyperprolactinemia.
Key facts
- Medical condition (new).name
- Hyperprolactinaemia
- Medical condition (new).synonyms
- Hyperprolactinemia, Chiari–Frommel syndrome
- Medical condition (new).image
- PRL structure.png
- Medical condition (new).caption
- Prolactin
- Medical condition (new).field
- Endocrinology
via Wikipedia infobox
Research
8,178 papers- Hyperprolactinemia and insulin resistance.Endokrynologia Polska · 2022
- Prolactin-secreting adenomas: pathogenesis, diagnosis, and management.The lancet. Diabetes & endocrinology · 2025
- [Hyperprolactinemia and prolactinemia--investigation and treatment].Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 2002
- Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials.Planta medica · 2013
- Hyperprolactinemia in children and adolescents and longterm follow-up results of prolactinoma cases: a single-centre experience.The Turkish journal of pediatrics · 2022
via PubMed
Wikidata facts
- Image
- PRL structure.png
Show 2 more facts
- NCI Thesaurus ID
- C113168
- exact match
- www.orpha.net/ORDO/Orphanet_397685
via Wikidata · CC0
~26 min read
Article
10 sectionsContents
- Signs and symptoms
- Causes
- Physiological causes
- Medications
- Specific diseases
- Diagnosis
- Treatment
- See also
- References
- External links
Hyperprolactinaemia (also spelled hyperprolactinemia) is a condition characterized by abnormally high levels of prolactin in the blood. In women, normal prolactin levels average to about 13 ng/mL, while in men, they average 5 ng/mL. The upper normal limit of serum prolactin is typically between 15 and 25 ng/mL for both men and women. Levels exceeding this range indicate hyperprolactinemia.
Prolactin (PRL) is a peptide hormone produced by lactotroph cells in the anterior pituitary gland. It plays a vital role in lactation and breast development. Hyperprolactinemia, characterized by abnormally high levels of prolactin, may cause galactorrhea (production and spontaneous flow of breast milk), infertility, and menstrual disruptions in women. In men, it can lead to hypogonadism, infertility and erectile dysfunction.