hypocalcaemia

Also known as hypocalcemia

Key facts

Medical condition (new).name: Hypocalcemia
Medical condition (new).image: Polfa Warszawa Calcium Chloratum 67mg-per-ml 10ml - stack.jpg
Medical condition (new).alt: Calcium chloride ampoules
Medical condition (new).field: Endocrinology
Medical condition (new).symptoms: Numbness, muscle spasms, seizures, confusion
Medical condition (new).complications: Cardiac arrest
Medical condition (new).causes: Hypoparathyroidism, vitamin D deficiency, kidney failure, pancreatitis, calcium channel blocker overdose, rhabdomyolysis, tumor lysis syndrome, bisphosphonates
Medical condition (new).diagnosis: Blood serum < 2.1 mmol/L (corrected calcium or ionized calcium)
Medical condition (new).treatment: Calcium supplements, vitamin D, magnesium sulfate.
Medical condition (new).frequency: ~18% of people in hospital

via Wikipedia infobox

Research

19,325 papers

via PubMed

Clinical Trials

112 registered

NANOT_YET_RECRUITING
WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-MakingFujian Medical University · NCT07043010
NARECRUITING
Usefulness of ICG Angiography-Guided Thyroidectomy for Preserving Parathyroid FunctionHospital Universitari de Bellvitge · NCT05573828
PHASE2TERMINATED
Studies With 1,25-DihydroxycholecalciferolNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · NCT00001151
NACOMPLETED
Open Thyroid Surgery With Pillow Versus no Pillow for Better Post-operative OutcomesThe University of Hong Kong · NCT01620151
RECRUITING
Quantitative Intra-operative Assessment of Parathyroid Perfusion Using Indocyanine Green (ICG) Fluorescence ImagingFujian Medical University · NCT07010341
NACOMPLETED
Comparison of Serum Calcium Level Between Preoperative Vitamin D and Non-vitamin D Regimen of Total Parathyroidectomy in End-stage Renal Failure Patients in Rajavithi HospitalDepartment of Medical Services Ministry of Public Health of Thailand · NCT04967469

via ClinicalTrials.gov

Wikidata facts

Show 3 more facts

Commons category: Hypocalcemia
NCI Thesaurus ID: C37973
exact match: purl.obolibrary.org/obo/HP_0002901

Sources (6)

via Wikidata · CC0

~5 min read

Article

9 sections

Contents

Signs and symptoms
Causes
Pathophysiology
Mechanism
Diagnosis
Management
See also
References
External links

Hypocalcemia is a medical condition characterized by low calcium levels in the blood serum. The normal range of blood calcium is typically between 2.1–2.6 mmol/L (8.8–10.7 mg/dL, 4.3–5.2 mEq/L), while levels less than 2.1 mmol/L are defined as hypocalcemic. Mildly low levels that develop slowly often have no symptoms. Otherwise symptoms may include numbness, muscle spasms, seizures, confusion, or in extreme cases cardiac arrest.

The most common cause for hypocalcemia is iatrogenic hypoparathyroidism. Other causes include other forms of hypoparathyroidism, vitamin D deficiency, kidney failure, pancreatitis, calcium channel blocker overdose, rhabdomyolysis, tumor lysis syndrome, and medications such as bisphosphonates or denosumab. Diagnosis should generally be confirmed by determining the corrected calcium or ionized calcium level. Specific changes may also be seen on an electrocardiogram (ECG).