Structure via PubChem · Public domain (PubChem)
zoledronic acid
Sign in to saveAlso known as ZOL, ZOL446, CGP-42446, CGP-42446A, (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid, (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid, zoledronic acid anhydrous, Zol
chemical compound
Chemical data
- Formula
- C5H10N2O7P2
- Molecular weight
- 272.09 g/mol
- IUPAC name
- (1-hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid
- SMILES
- C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O
- InChIKey
- XRASPMIURGNCCH-UHFFFAOYSA-N
- XLogP
- -4.3
- Polar surface area
- 153 Ų
- H-bond donors
- 5
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Research
6,636 papers- Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2001
- Zoledronic acid and fracture risk: a meta-analysis of 12 randomized controlled trials.European review for medical and pharmacological sciences · 2021
- Zoledronic acid.Drugs · 2001
- Zoledronic acid for the treatment of prostate cancer.Expert opinion on pharmacotherapy · 2019
- Zoledronic Acid: Pleiotropic Anti-Tumor Mechanism and Therapeutic Outlook for Osteosarcoma.Current drug targets · 2018
via PubMed