Structure via PubChem · Public domain (PubChem)
pamidronic acid
Sign in to saveAlso known as ARD233, Aredia®, CGP-23339AE, pamidronate, Acide pamidronique, Acidum pamidronicum, Pamidronate
chemical compound
In the Vinony graph
Within Vinony's link graph, pamidronic acid is referenced by 43 other articles, and connects out to intravenous infusion and defusion, nitrogen and cancer.
Vinony files it under Bisphosphonates, ECHA InfoCard ID from Wikidata and Farnesyl pyrophosphate synthase inhibitors.
Its subject is documented across 18 Wikipedia language editions.
Chemical data
- Formula
- C3H11NO7P2
- Molecular weight
- 235.07 g/mol
- IUPAC name
- (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
- SMILES
- C(CN)C(O)(P(=O)(O)O)P(=O)(O)O
- InChIKey
- WRUUGTRCQOWXEG-UHFFFAOYSA-N
- XLogP
- -6.9
- Polar surface area
- 161 Ų
- H-bond donors
- 6
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1991
- Admin. routes
- parenteral
- Indications
- bone disease, multiple myeloma, osteoporosis, Low back pain
via ChEMBL · EBI
Research
3,481 papers- Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2001
- Atrial fibrillation in patients treated with intravenous zoledronic or pamidronic acid: a pharmacoepidemiological study.European journal of endocrinology · 2021
- Preparation, Optimisation, and In Vitro Evaluation of [(18)F]AlF-NOTA-Pamidronic Acid for Bone Imaging PET.Molecules (Basel, Switzerland) · 2022
- Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2003
- Preparation, Characterization, and Radiolabeling of [(68)Ga]Ga-NODAGA-Pamidronic Acid: A Potential PET Bone Imaging Agent.Molecules (Basel, Switzerland) · 2020
via PubMed
Wikidata facts
- Subclass of
- bisphosphonate
- Mass
- 235.001
- Has use
- medication
Show 5 more facts
- defined daily dose
- 60
- chemical formula
- C₃H₁₁NO₇P₂
- World Health Organisation international non-proprietary name
- pamidronic acid
- medical condition treated
- mammary Paget's disease
- canonical SMILES
- C(CN)C(O)(P(=O)(O)O)P(=O)(O)O
Sources (6)
via Wikidata · CC0
Connections
intravenous infusion and defusion
Entity
nitrogen
Entity
cancer
Entity
bone
Entity
calcium
Entity
medication
Entity
International Standard Book Number
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kidney
Entity
digital object identifier
Entity
chemical formula
Entity
vitamin D
Entity
osteoporosis
Entity
molar mass
Entity
OCLC, Inc.
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nausea
Entity
PubMed
Entity
excretion
Entity
CAS Registry Number
Entity
multiple myeloma
Entity
PubChem
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