ibandronic acid

Chemical data

Formula

C9H23NO7P2

Molecular weight

319.23 g/mol

IUPAC name

[1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl]phosphonic acid

SMILES

CCCCCN(C)CCC(O)(P(=O)(O)O)P(=O)(O)O

InChIKey

MPBVHIBUJCELCL-UHFFFAOYSA-N

XLogP

-4.1

Polar surface area

139 Ų

H-bond donors

5

H-bond acceptors

8

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

1996

Admin. routes

oral, parenteral

Indications

postmenopausal osteoporosis, osteoporosis, bone disease, multiple myeloma

via ChEMBL · EBI

• Osteoporosis treatment: why ibandronic acid?Expert opinion on pharmacotherapy · 2013
• Ibandronic acid: a review of its use in the treatment of bone metastases of breast cancer.Drugs · 2006
• Oral ibandronic acid.IDrugs : the investigational drugs journal · 2005
• 68 Ga-DOTA-Ibandronic Acid PET/CT in a Patient With Chemotherapy-Induced Salivary Gland Hypofunction.Clinical nuclear medicine · 2024
• Zoledronic acid is more efficient than ibandronic acid in the treatment of symptomatic bone marrow lesions of the knee.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020

via PubMed

Wikidata facts

Subclass of

bisphosphonate

Has part

carbon

Mass

319.095

Has use

medication

via Wikidata · CC0