Structure via PubChem · Public domain (PubChem)
clodronic acid
Sign in to saveAlso known as Dichloromethylene-1,1-bisphosphonic acid, (Dichloromethylene)diphosphonic acid, (Dichloromethylene)bisphosphonic acid, (Dichloro-phosphono-methyl)-phosphonic acid, Dichloromethanediphosphonic acid, Dichloromethylene-1,1-diphosphonic acid, Dichloromethylidene diphosphonate, Clodronsaeure
chemical compound
Chemical data
- Formula
- CH4Cl2O6P2
- Molecular weight
- 244.89 g/mol
- IUPAC name
- [dichloro(phosphono)methyl]phosphonic acid
- SMILES
- C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl
- InChIKey
- ACSIXWWBWUQEHA-UHFFFAOYSA-N
- XLogP
- -2.1
- Polar surface area
- 115 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- bone disease, brachial plexus neuropathy
via ChEMBL · EBI
Research
1,845 papers- Clodronic acid formulations available in Europe and their use in osteoporosis: a review.Clinical drug investigation · 2009
- Clodronic acid in the treatment of postmenopausal osteoporosis.Clinical drug investigation · 2007
- [Use of clodronic acid in mineral metabolism conditions: state of the art in 2000].Minerva medica · 2001
- Clodronate.Bone · 2021
- Effects of zoledronic acid versus clodronic acid on skeletal morbidity in patients with newly diagnosed multiple myeloma (MRC Myeloma IX): secondary outcomes from a randomised controlled trial.The Lancet. Oncology · 2011
via PubMed
Wikidata facts
- Subclass of
- bisphosphonate
- Has part
- carbon
- Mass
- 243.886016
- Has use
- medication
Show 3 more facts
- chemical formula
- CH₄Cl₂O₆P₂
- canonical SMILES
- C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl
- World Health Organisation international non-proprietary name
- clodronic acid
via Wikidata · CC0
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via Wikidata sitelinks · CC0