IMMT

Also known as HMP, MINOS2, P87, P87/89, P89, PIG52, Mic60, PIG4

Mitochondrial inner membrane protein is a protein that in humans is encoded by the IMMT gene.)

Gene data

IMMT

Name: inner membrane mitochondrial protein
Type: protein-coding
Position: 86,142,798–86,195,626 (−)
Aliases: HMP, MICOS60, MINOS2, Mic60, P87, P87/89, P89, PIG4, PIG52
Ensembl: ENSG00000132305
RefSeq RNA: NM_001100169.2, NM_001100170.2, NM_001400086.1, NM_001400087.1, NM_001400088.1
RefSeq protein: NP_001093639.1, NP_001093640.1, NP_001387015.1, NP_001387016.1, NP_001387017.1

Enables RNA binding activity. Involved in cristae formation. Located in mitochondrial inner membrane. Part of MICOS complex. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

inner mitochondrial membrane organization cristae formation cristae formation

Article

6 sections

Contents

Function
Interactions
Localisation/Import
Interactions
References
Further reading

Mitochondrial inner membrane protein is a protein that in humans is encoded by the IMMT gene.)

IMMT encodes an inner mitochondrial membrane (IMM) protein in the nucleus. It is posttranslational transported to the IMM. Mic60/Mitofilin (encoded by the IMMT gene) is a core subunit of the MICOS-complex, directly located next to cristae junctions (CJ). Human Mic60 exists in two isoforms of different size, anchored to the IMM via its N-terminus, while most of the protein is located to the inner mitochondrial space (IMS).