OPA1

Also known as MGM1, NPG, NTG, largeG, Optic atrophy 1, BERHS, MTDPS14, OPA1, mitochondrial dynamin like GTPase

protein-coding gene in the species Homo sapiens

Gene data

OPA1

Name: OPA1 mitochondrial dynamin like GTPase
Type: protein-coding
Aliases: BERHS, MGM1, MTDPS14, MTDPS14A, MTDPS14B, NPG, NTG, largeG

The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017].

via MyGene.info