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indium-111

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Also known as In-111, 111In, indium in-111, Indium (111 In), Indium In-111

Indium-111 (111In) is a radioactive isotope of indium (In). It decays by electron capture to stable cadmium-111 with a half-life of 2.8048 days. The isotope is produced by proton irradiation of a cadmium target (112Cd(p,2n) or 111Cd(p,n)) in a cyclotron, as recommended by International Atomic Energy Agency (IAEA). The former method is more commonly used as it results in a higher level of radionuclide purity.

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Encyclopedic overview

5 sections
Contents
  • Uses in nuclear medicine
  • <sup>111</sup>In labeled antibodies
  • <sup>111</sup>In labeled peptides
  • See also
  • References

Indium-111 (111In) is a radioactive isotope of indium (In). It decays by electron capture to stable cadmium-111 with a half-life of 2.8048 days. The isotope is produced by proton irradiation of a cadmium target (112Cd(p,2n) or 111Cd(p,n)) in a cyclotron, as recommended by International Atomic Energy Agency (IAEA). The former method is more commonly used as it results in a higher level of radionuclide purity.

Indium-111 is commonly used in nuclear medicine diagnostic imaging by radiolabeling targeted molecules or cells. During its radioactive decay, it emits gamma (γ) photons which can be imaged using planar or single-photon emission computed tomography (SPECT) gamma cameras (primary energies: 171.3 keV (91%) and 245.4 keV (94%)).

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