Skip to content
isoflurane

Structure via PubChem · Public domain (PubChem)

EntityQ413918· pop 36· linked from 2,721 articles

isoflurane

Sign in to save

Also known as Compound 469, Forane, Aerrane, 1-chloro-2,2,2-Trifluoroethyl difluoromethyl ether, Forene, Isoflurano, Isofluranum

Isoflurane, sold under the brand name Forane among others, is a halogenated ether used as a general anesthetic. It can be used to start or maintain anesthesia; however, other medications are often used to start anesthesia, due to airway irritation with isoflurane. Isoflurane is a inhalational anesthetic given via inhalation.

Key facts

Drug.Verifiedfields
changed
Drug.Watchedfields
changed
Drug.verifiedrevid
443883276
Drug.image
Isoflurane.svg
Drug.image_class
skin-invert-image
Drug.width
150
Drug.image2
Isoflurane-3D-vdW.png
Drug.image_class2
bg-transparent
Drug.width2
150
Drug.tradename
Forane, others
Drug.DailyMedID
Isoflurane
Drug.pregnancy_AU
B3
Drug.routes_of_administration
Respiratory
Drug.class
Inhalational anesthetic
Drug.ATC_prefix
N01
Drug.ATC_suffix
AB06
Drug.legal_BR
C1
Drug.legal_UK
POM

via Wikipedia infobox

Chemical data

Formula
C3H2ClF5O
Molecular weight
184.49 g/mol
IUPAC name
2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
SMILES
C(C(F)(F)F)(OC(F)F)Cl
InChIKey
PIWKPBJCKXDKJR-UHFFFAOYSA-N
XLogP
2.1
Polar surface area
9.2 Ų
H-bond donors
0
H-bond acceptors
6
Formal charge
0

via PubChem

~5 min read

Encyclopedic overview

10 sections
Contents
  • Medical uses
  • Mechanism of action
  • Adverse effects
  • Elderly
  • Anesthetic physical properties
  • History
  • Environment
  • Veterinary use
  • References
  • External links

Isoflurane, sold under the brand name Forane among others, is a halogenated ether used as a general anesthetic. It can be used to start or maintain anesthesia; however, other medications are often used to start anesthesia, due to airway irritation with isoflurane. Isoflurane is a inhalational anesthetic given via inhalation.

Isoflurane was approved for medical use in the United States in 1979. It is on the World Health Organization's List of Essential Medicines.

Excerpted from Wikipedia’s “isoflurane” article, available under the CC BY-SA 4.0 licence.