itopride

Also known as N-(p-(2-(Dimethylamino)ethoxy)benzyl)veratramide

Itopride (INN; brand name Ganaton) is a prokinetic benzamide derivative. These drugs inhibit dopamine and acetylcholine esterase enzyme and have a gastrokinetic effect. Itopride is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions. It is a combined D2 receptor antagonist and acetylcholinesterase inhibitor. Itopride is the dimethoxy analog of trimethobenzamide.

Key facts

Drug.KEGG: D08094
Drug.KEGG2: D02729
Drug.Verifiedfields: changed
Drug.verifiedrevid: 444538072
Drug.image: Itopride.svg
Drug.image_class: skin-invert-image
Drug.width: 260
Drug.image2: 3D Itopride.png
Drug.image_class2: bg-transparent
Drug.tradename: Ganaton
Drug.legal_status: Rx-only
Drug.routes_of_administration: By mouth
Drug.ATC_prefix

Article

10 sections

Contents

Medical uses
Adverse drug reactions
Cardiac studies
Pharmacology
Pharmacokinetics
Mechanism of action
Society and culture
Names
References
External links

==Medical uses== thumb|240px|A blister package of Ganaton (Itopride) 50 mg tablets intended for distribution in the Slovak Republic. Typically, itopride is indicated in the treatment of GI symptoms caused by reduced GI motility: dyspepsia of a non-ulcer/dysmotility type (gastric "fullness", discomfort, and possible pain) gastroparesis (delayed gastric emptying) anorexia heartburn regurgitation bloating nausea and vomiting other possible gastric, prolactin, or dopamine related conditions