Structure via PubChem · Public domain (PubChem)
ketazocine
Sign in to saveKetazocine (INN), also known as ketocyclazocine, is a benzomorphan derivative used in opioid receptor research. Ketazocine, for which the receptor is named, is an exogenous opioid that binds to the κ opioid receptor.
Chemical data
- Formula
- C18H23NO2
- Molecular weight
- 285.4 g/mol
- IUPAC name
- (1R,9S,13R)-10-(cyclopropylmethyl)-4-hydroxy-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-8-one
- SMILES
- C[C@H]1[C@H]2C(=O)C3=C([C@@]1(CCN2CC4CC4)C)C=C(C=C3)O
- InChIKey
- HQBZLVPZOGIAIQ-SDDDUWNISA-N
- XLogP
- 3.5
- Polar surface area
- 40.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 285.173
Show 4 more facts
- chemical formula
- C₁₈H₂₃NO₂
- canonical SMILES
- CC1C2C(=O)C3=C(C1(CCN2CC4CC4)C)C=C(C=C3)O
- isomeric SMILES
- C[C@H]1[C@H]2C(=O)C3=C([C@@]1(CCN2CC4CC4)C)C=C(C=C3)O
- Commons category
- Ketazocine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Ketazocine (INN), also known as ketocyclazocine, is a benzomorphan derivative used in opioid receptor research. Ketazocine, for which the receptor is named, is an exogenous opioid that binds to the κ opioid receptor.
Activation of this receptor is known to cause sleepiness, a decrease in pain sensation and (potentially) dysphoria, paranoia, and hallucinations. It also causes an increase in urine production because it inhibits the release of vasopressin.
Excerpted from Wikipedia’s “ketazocine” article, available under the CC BY-SA 4.0 licence.