KIRREL1
Sign in to saveAlso known as NEPH1, KIRREL, kin of IRRE like (Drosophila), Kin of IRRE-like protein 1, kirre like nephrin family adhesion molecule 1, NPHS23
Kin of IRRE-like protein 1, also known as NEPH1, is a protein that in humans is encoded by the KIRREL gene.
In the Vinony graph
Within Vinony's link graph, KIRREL1 is referenced by 7 other articles, and connects out to PubMed, Online Mendelian Inheritance in Man and human chromosome 1.
It is catalogued under the topic Genes on human chromosome 1.
Its subject is documented across 6 Wikipedia language editions.
Gene data
KIRREL1- Name
- kirre like nephrin family adhesion molecule 1
- Type
- protein-coding
- Position
- 157,993,273–158,100,262 (+)
- Aliases
- KIRREL, NEPH1, NPHS23
- Ensembl
- ENSG00000183853
- RefSeq RNA
- NM_001286349.2, NM_018240.7, XM_005245305.6, XM_047424310.1, XM_047424312.1
- RefSeq protein
- NP_001273278.1, NP_060710.3, XP_005245362.1, XP_047280266.1, XP_047280268.1
NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
kirre like nephrin family adhesion molecule 1
- Symbol
- KIRREL1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:157,993,273-158,100,262
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 10089
- genetic association
- obesity
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55243
- genomic end
- 158070052
- genomic start
- 157963063
- chromosome
- human chromosome 1
- cytogenetic location
- 1q23.1
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Kin of IRRE-like protein 1, also known as NEPH1, is a protein that in humans is encoded by the KIRREL gene.
== Function ==
Excerpted from Wikipedia’s “KIRREL1” article, available under the CC BY-SA 4.0 licence.