LASP1
Sign in to saveAlso known as MLN50, LIM and SH3 protein 1, LASP-1
LIM and SH3 domain protein 1 is a protein that in humans is encoded by the LASP1 gene.
In the Vinony graph
Within Vinony's link graph, LASP1 is referenced by 5 other articles, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 17.
Its subject is documented across 6 Wikipedia language editions.
Gene data
LASP1- Name
- LIM and SH3 protein 1
- Type
- protein-coding
- Position
- 38,869,185–38,921,771 (+)
- Aliases
- Lasp-1, MLN50
- Ensembl
- ENSG00000002834
- RefSeq RNA
- NM_001271608.2, NM_006148.4, NR_073384.2, XM_047435965.1
- RefSeq protein
- NP_001258537.1, NP_006139.1, XP_047291921.1
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
LIM and SH3 protein 1
- Symbol
- LASP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:38,869,185-38,921,771
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein LASP1 PDB 1zfo.png
Show 9 more facts
- HomoloGene ID
- 4480
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3927
- genomic end
- 37078023
- genomic start
- 37026112
- expressed in
- thymus
- chromosome
- human chromosome 17
- cytogenetic location
- 17q12
- Commons category
- LASP-1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
LIM and SH3 domain protein 1 is a protein that in humans is encoded by the LASP1 gene.
This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization.
Excerpted from Wikipedia’s “LASP1” article, available under the CC BY-SA 4.0 licence.