LIMS2
Sign in to saveAlso known as PINCH-2, PINCH2, LGMD2W, LIM zinc finger domain containing 2, MDRCMTT
LIM zinc finger domain containing 2 is a protein that in humans is encoded by the LIMS2 gene.
In the Vinony graph
Within Vinony's link graph, LIMS2 is referenced by 2 other articles, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 2.
Its subject is documented across 5 Wikipedia language editions.
Gene data
LIMS2- Name
- LIM zinc finger domain containing 2
- Type
- protein-coding
- Position
- 127,638,381–127,681,786 (−)
- Aliases
- LGMD2W, MDRCMTT, PINCH-2, PINCH2
- Ensembl
- ENSG00000072163
- RefSeq RNA
- NM_001136037.4, NM_001161403.3, NM_001161404.2, NM_001256542.2, NM_017980.5
- RefSeq protein
- NP_001129509.2, NP_001154875.1, NP_001154876.1, NP_001243471.1, NP_060450.2
This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
LIM zinc finger domain containing 2
- Symbol
- LIMS2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:127,638,381-127,681,786
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 41214
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55679
- genomic end
- 128439360
- genomic start
- 128395956
- chromosome
- human chromosome 2
- cytogenetic location
- 2q14.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
LIM zinc finger domain containing 2 is a protein that in humans is encoded by the LIMS2 gene.
==Function==
Excerpted from Wikipedia’s “LIMS2” article, available under the CC BY-SA 4.0 licence.