MORC2
Sign in to saveAlso known as ZCW3, ZCWCC1, CMT2Z, MORC family CW-type zinc finger 2, DIGFAN
MORC family CW-type zinc finger protein 2 is a protein that in humans is encoded by the MORC2 gene.
In the Vinony graph
Within Vinony's link graph, MORC2 is referenced by 4 other articles, and connects out to PubMed, human chromosome 22 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 22.
Its subject is documented across 5 Wikipedia language editions.
Gene data
MORC2- Name
- MORC family CW-type zinc finger 2
- Type
- protein-coding
- Position
- 30,925,130–30,969,662 (−)
- Aliases
- CMT2Z, DIGFAN, ZCW3, ZCWCC1
- Ensembl
- ENSG00000133422
- RefSeq RNA
- NM_001303256.3, NM_001303257.2, NM_014941.3, XM_011530004.3, XM_017028667.3
- RefSeq protein
- NP_001290185.1, NP_001290186.1, NP_055756.1, XP_011528306.1, XP_016884156.1
This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
MORC family CW-type zinc finger 2
- Symbol
- MORC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:30,925,130-30,969,662
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 8966
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/22880
- genomic end
- 30968774
- genomic start
- 31321117
- chromosome
- human chromosome 22
- cytogenetic location
- 22q12.2
- expressed in
- gastric mucosa
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
MORC family CW-type zinc finger protein 2 is a protein that in humans is encoded by the MORC2 gene.
==References==
Excerpted from Wikipedia’s “MORC2” article, available under the CC BY-SA 4.0 licence.