皮下脂肪萎縮症
Sign in to saveLipoatrophy is the term describing the localized loss of fat tissue. This may occur as a result of subcutaneous injections of insulin in the treatment of diabetes, from the use of human growth hormone or from subcutaneous injections of copaxone used for the treatment of multiple sclerosis. In the latter case, an injection may produce a small dent at the injection site. Lipoatrophy occurs in HIV-associated lipodystrophy, one cause of which is an adverse drug reaction that is associated with some antiretroviral medications.
Health references
- ICD-10
- E88.10 — Lipodystrophy, unspecified
Clinical Trials
216 registered- NACOMPLETEDA Study of Amprenavir in Patients With Protease Inhibitor-Related ComplicationsGlaxo Wellcome · NCT00002417
- NACOMPLETED[68Ga]Ga-GZP PET for Early Response Prediction in Colorectal Cancer During Neoadjuvant TherapyUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology · NCT06982053
- COMPLETEDPerformance and Safety of the Lipo-transfer Cannulas in Patients Underlying Lipofilling TreatmentAesthetic Group · NCT06089759
- AVAILABLEExpanded Access Metreleptin StudyUniversity of Michigan · NCT02404896
- COMPLETEDMetabolism and Body Shape of Healthy Children and Children With Chronic InfectionsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · NCT00001142
- NACOMPLETEDEplerenone in HIV Associated Abdominal Fat AccumulationMassachusetts General Hospital · NCT01405456
Article · 日本語
リポアトロフィー（英: Lipoatrophy）とは、局所の脂肪組織が失われる病態を指す。糖尿病治療のためにインスリンを皮下注射した部位や、多発性硬化症治療目的にグラチラマーを注射した部位、ヒト成長ホルモンを皮下注射した部位などに見られることがある。グラチラマーの場合、投与部位に小さな凹みが目視できる。リポアトロフィーはHIVのHAART療法の副作用として生ずるの一症状としても見られる。 より広い意味で全身の脂肪組織が失われる病態は、リポジストロフィーと呼ばれる。
Abstract from DBpedia / Wikipedia · CC BY-SA