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GeneQ18035390· pop 5· linked from 2 articles

Also known as FIGLER7, GAC1, LRANK1, LRRN5, leucine rich repeat neuronal 2

Leucine-rich repeat neuronal protein 2 is a protein that in humans is encoded by the LRRN2 gene.

Gene data

LRRN2
Name
leucine rich repeat neuronal 2
Type
protein-coding
Aliases
FIGLER7, GAC1, LRANK1, LRRN5

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

leucine rich repeat neuronal 2

Symbol
LRRN2
Biotype
Protein coding
Organism
Homo sapiens
Location
1:204,617,170-204,685,745
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
21274
genomic end
204685738
genomic start
204586298
cytogenetic location
1q32.1
Sources (3)

via Wikidata · CC0

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Leucine-rich repeat neuronal protein 2 is a protein that in humans is encoded by the LRRN2 gene.

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

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