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GeneQ18035390· pop 5· linked from 2 articles

Also known as FIGLER7, GAC1, LRANK1, LRRN5, leucine rich repeat neuronal 2

Leucine-rich repeat neuronal protein 2 is a protein that in humans is encoded by the LRRN2 gene.

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Vinony's link graph records 2 inbound references to LRRN2, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 1.

Vinony links it to 5 Wikipedia language editions.

Gene data

LRRN2
Name
leucine rich repeat neuronal 2
Type
protein-coding
Position
204,617,170–204,685,745 (−)
Aliases
FIGLER7, GAC1, LRANK1, LRRN5
RefSeq RNA
NM_006338.3, NM_201630.2
RefSeq protein
NP_006329.2, NP_963924.1

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

leucine rich repeat neuronal 2

Symbol
LRRN2
Biotype
Protein coding
Organism
Homo sapiens
Location
1:204,617,170-204,685,745
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
21274
found in taxon
Homo sapiens
genomic end
204685738
genomic start
204586298
cytogenetic location
1q32.1
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Leucine-rich repeat neuronal protein 2 is a protein that in humans is encoded by the LRRN2 gene.

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Excerpted from Wikipedia’s “LRRN2” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

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