LTA4H
Sign in to saveAlso known as leukotriene A4 hydrolase
protein-coding gene in the species Homo sapiens
Gene data
LTA4H- Name
- leukotriene A4 hydrolase
- Type
- protein-coding
The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015].
via MyGene.info
Gene · Ensembl
leukotriene A4 hydrolase
- Symbol
- LTA4H
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:96,000,298-96,043,523
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- 1HS6.png
Show 6 more facts
- HomoloGene ID
- 6820
- exact match
- identifiers.org/ncbigene/4048
- genomic end
- 96437298
- genomic start
- 96000753
- cytogenetic location
- 12q23.1
- Commons category
- Leukotriene-A4 hydrolase
via Wikidata · CC0
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