lucanthone
Sign in to saveAlso known as 1-diethylaminoethylethylamino-4-methyl-thioxanthenone, 1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one, 1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one, Lucanthonum, Lucantona
Lucanthone (Miracil D, Myracyl D) is a drug used to treat parasitic diseases such as schistosomiasis, which was invented in 1938 by Hans Mauss and colleagues at Bayer AG. It is a prodrug and is converted to the active metabolite hycanthone. It is no longer commonly used in humans due to hepatotoxicity, especially after the subsequent development of safer drugs with similar efficacy such as praziquantel.
Research
329 papersvia PubMed
Wikidata facts
- Mass
- 340.160934
Show 4 more facts
- Commons category
- Lucanthone
- World Health Organisation international non-proprietary name
- lucanthone
- chemical formula
- C₂₀H₂₄N₂OS
- canonical SMILES
- CCN(CC)CCNC1=C2C(=C(C=C1)C)SC3=CC=CC=C3C2=O
Sources (2)
via Wikidata · CC0
~2 min read
Article
4 sectionsContents
- Mechanism of action
- Research
- Synthesis
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 443927477 | IUPAC_name = 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one | image = Lucanthone.png | image_class = skin-invert-image | width = 150 | image2 = Lucanthone molecule ball.png | image_class2 = bg-transparent | width2 = 220 | alt2 = Ball-and-stick model of the lucanthone molecule
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =