Structure via PubChem · Public domain (PubChem)
lurasidone
Sign in to saveAlso known as Latuda®, SM-13496, Lurasidonum, Lurasidona
Lurasidone, sold under the brand name Latuda among others, is an atypical antipsychotic medication used to treat schizophrenia and bipolar depression. It is taken by mouth.
Key facts
- Drug.image
- Lurasidone.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.caption
- Above: molecular structure of lurasidone Below: 3D representation of a lurasidone molecule
- Drug.image2
- Lurasidone 3D ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250
- Drug.alt2
- Ball-and-stick model of the lurasidone molecule
- Drug.tradename
- Latuda, others
- Drug.MedlinePlus
- a611016
- Drug.DailyMedID
- Lurasidone
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- By mouth
- Drug.class
- Atypical antipsychotic
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- AE05
- Drug.legal_AU
- S4
- Drug.legal_BR
- C1
via Wikipedia infobox
Chemical data
- Formula
- C28H36N4O2S
- Molecular weight
- 492.7 g/mol
- IUPAC name
- (1R,2S,6R,7S)-4-[[(1R,2R)-2-[[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl]cyclohexyl]methyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
- SMILES
- C1CC[C@H]([C@@H](C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)[C@H]6[C@@H]7CC[C@@H](C7)[C@H]6C5=O
- InChIKey
- PQXKDMSYBGKCJA-CVTJIBDQSA-N
- XLogP
- 5.4
- Polar surface area
- 85 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 492.256
Show 6 more facts
- defined daily dose
- 60
- chemical formula
- C₂₈H₃₆N₄O₂S
- canonical SMILES
- C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
- isomeric SMILES
- C1CC[C@H]([C@@H](C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)[C@H]6[C@@H]7CC[C@@H](C7)[C@H]6C5=O
- World Health Organisation international non-proprietary name
- lurasidone
- Commons category
- Lurasidone
via Wikidata · CC0
~14 min read
Article
14 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Discontinuation
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- History
- Society and culture
- Regulatory approval
- Brand names
- References
- External links
Lurasidone, sold under the brand name Latuda among others, is an atypical antipsychotic medication used to treat schizophrenia and bipolar depression. It is taken by mouth.
Common side effects include sedation, indigestion, nausea, and insomnia. At higher dosages, there is an increased risk for restlessness and movement problems. Serious side effects are valid for all atypical antipsychotics and may include the potentially permanent movement disorder tardive dyskinesia, as well as neuroleptic malignant syndrome, angioedema, and high blood sugar levels. Although lurasidone is less likely to cause high blood sugar levels in most patients, hyperosmolar hyperglycemic syndrome may occur. In older people with psychosis as a result of dementia, it may increase the risk of dying. Use during pregnancy is of unclear safety.