methicillin
Also known as Celpillina, Staphcillin, Methicillinum, Methycillin, (2,6-Dimethoxyphenyl)penicillin, 6-(2,6-Dimethoxybenzamido)penicillanic acid, 6beta-(2,6-Dimethoxybenzamido)penicillanic acid
Methicillin (USAN), also known as meticillin (INN), is a narrow-spectrum β-lactam antibiotic of the penicillin class.
Chemical data
- Formula
- C17H20N2O6S
- Molecular weight
- 380.4 g/mol
- IUPAC name
- (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- SMILES
- CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)O)C
- InChIKey
- RJQXTJLFIWVMTO-TYNCELHUSA-N
- XLogP
- 1.2
- Polar surface area
- 130 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
55,949 papersArticle
6 sectionsContents
- Medical uses
- Spectrum of activity
- Mechanism of action
- Medicinal chemistry
- History
- References
Methicillin (USAN), also known as meticillin (INN), is a narrow-spectrum β-lactam antibiotic of the penicillin class.
Methicillin was discovered in 1960.