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mezlocillin
EntityQ3307752· pop 16· linked from 194 articles

mezlocillin

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Also known as Multocillin, Mezlocilina, (2S,5R,6R)-3,3-Dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, Mezlocilline, Mezlocillinum, Mezlin, 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid

Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis.

Research

1,066 papers

via PubMed

Wikidata facts

Mass
539.114
Show 6 more facts
chemical formula
C₂₁H₂₅N₅O₈S₂
Commons category
Mezlocillin
isomeric SMILES
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)N4CCN(C4=O)S(=O)(=O)C)C(=O)O)C
canonical SMILES
CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)N4CCN(C4=O)S(=O)(=O)C)C(=O)O)C
World Health Organisation international non-proprietary name
mezlocillin
defined daily dose
6
Sources (5)

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Article

8 sections
Contents
  • Mechanism of action
  • Susceptible organisms
  • Gram-negative
  • Gram-positive
  • Synthesis
  • References
  • Further reading
  • External links

Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis.

==Mechanism of action==

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