mezlocillin
Sign in to saveAlso known as Multocillin, Mezlocilina, (2S,5R,6R)-3,3-Dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, Mezlocilline, Mezlocillinum, Mezlin, 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid
Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis.
Research
1,066 papersvia PubMed
Wikidata facts
- Mass
- 539.114
- Has use
- medication
Show 7 more facts
- chemical formula
- C₂₁H₂₅N₅O₈S₂
- Commons category
- Mezlocillin
- isomeric SMILES
- CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)N4CCN(C4=O)S(=O)(=O)C)C(=O)O)C
- canonical SMILES
- CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)N4CCN(C4=O)S(=O)(=O)C)C(=O)O)C
- World Health Organisation international non-proprietary name
- mezlocillin
- defined daily dose
- 6
- subject has role
- bactericide
via Wikidata · CC0
~2 min read
Encyclopedic overview
8 sectionsContents
- Mechanism of action
- Susceptible organisms
- Gram-negative
- Gram-positive
- Synthesis
- References
- Further reading
- External links
Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis.
==Mechanism of action==
Excerpted from Wikipedia’s “mezlocillin” article, available under the CC BY-SA 4.0 licence.