mitobronitol

Chemical data

Formula

C6H12Br2O4

Molecular weight

307.96 g/mol

IUPAC name

(2S,3S,4S,5S)-1,6-dibromohexane-2,3,4,5-tetrol

SMILES

C([C@H]([C@H]([C@@H]([C@@H](CBr)O)O)O)O)Br

InChIKey

VFKZTMPDYBFSTM-KVTDHHQDSA-N

XLogP

-0.3

Polar surface area

80.9 Ų

H-bond donors

4

H-bond acceptors

4

Formal charge

0

via PubChem

Drug data · ChEMBL

Molecule type

Small molecule

via ChEMBL · EBI

• Mitobronitol: an alkylating agent that does not induce extra leukemia cases if applied as pulse therapy for polycythemia vera.Annals of the New York Academy of Sciences · 1985
• Non-supralethal mitobronitol/cytarabine/cyclophosphamide conditioning without irradiation before bone marrow transplantation for accelerated chronic granulocytic leukemia: apparent absence of acute graft-versus-host disease.Leukemia · 1993
• Multiple granulocytic sarcomas in essential thrombocythemia.International journal of hematology · 2006
• Comparison of the lymphoid toxicities of mitobronitol and busulphan in mice: reduced B cell toxicity and improved thymic recovery as possible contributors to the reduced risk for complications following BMT with mitobronitol preconditioning.Leukemia · 1997
• Anticancer chemotherapy.British medical journal (Clinical research ed.) · 1983

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

305.910233064

Has use

medication

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