monatepil
Sign in to saveMonatepil is a calcium channel blocker and α1-adrenergic receptor antagonist used as an antihypertensive.
Research
31 papers- Antihypertensive, antiatherosclerotic, and plasma lipid-lowering effects of monatepil, a novel calcium antagonist with alpha 1-adrenoceptor-blocking activity in experimental animals.American journal of hypertension · 1994
- Newer antihypertensive drugs.Current opinion in cardiology · 1995
- Effects of monatepil, a novel calcium antagonist with alpha 1-adrenergic blocking activity, on the low-density lipoprotein receptor in human skin fibroblasts.Cardiovascular drugs and therapy · 1997
- Inhibitory effect of monatepil maleate on acyl-CoA:cholesterol acyltransferase activity in the liver of cholesterol-fed Japanese monkeys.American journal of hypertension · 1997
- Effects of monatepil maleate, a new Ca2+ channel antagonist with alpha1-adrenoceptor antagonistic activity, on cholesterol absorption and catabolism in high cholesterol diet-fed rabbits.Japanese journal of pharmacology · 1998
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 475.209
Show 4 more facts
- canonical SMILES
- C1CN(CCN1CCCC(=O)NC2C3=CC=CC=C3CSC4=CC=CC=C24)C5=CC=C(C=C5)F
- chemical formula
- C₂₈H₃₀FN₃OS
- subject has role
- calcium channel blocker
- Commons category
- Monatepil
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Monatepil is a calcium channel blocker and α1-adrenergic receptor antagonist used as an antihypertensive.
==Synthesis== The synthesis of monatepil was first disclosed in patents filed by Dainippon Pharmaceutical. upright=2|class=skin-invert-image
Excerpted from Wikipedia’s “monatepil” article, available under the CC BY-SA 4.0 licence.