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morphogenesis
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Morphogenesis (from the Greek morphê shape and genesis creation, literally "the generation of form") is the biological process that causes a cell, tissue, or organism to develop its shape. It is one of three fundamental aspects of developmental biology, along with the control of tissue growth and the patterning of cellular differentiation.
Research
498,272 papers- Gastrulation morphogenesis in synthetic systems.Seminars in cell & developmental biology · 2023
- Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion.Cell · 2021
- Epithelial morphogenesis in organoids.Current opinion in genetics & development · 2022
- Morphogenesis.Cell · 1999
- Blastocoel morphogenesis: A biophysics perspective.Seminars in cell & developmental biology · 2022
via PubMed
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Article
15 sectionsContents
- History
- Genetic and molecular basis
- Cellular basis
- Cell-to-cell adhesion
- Extracellular matrix
- Cell contractility
- Branching morphogenesis
- Cancer morphogenesis
- Virus morphogenesis
- Computer models
- See also
- Notes
- References
- Further reading
- External links
Morphogenesis (from the Greek morphê shape and genesis creation, literally "the generation of form") is the biological process that causes a cell, tissue, or organism to develop its shape. It is one of three fundamental aspects of developmental biology, along with the control of tissue growth and the patterning of cellular differentiation.
The process controls the organized spatial distribution of cells during the embryonic development of an organism. Morphogenesis can take place also in a mature organism, such as in the normal maintenance of tissue by stem cells or in regeneration of tissues after damage. Cancer is an example of a pathological process of tissue morphogenesis, characterized by significant abnormalities. Morphogenesis also describes the development of unicellular life forms that do not have an embryonic stage in their life cycle. Morphogenesis is essential for the evolution of new forms.