Structure via PubChem · Public domain (PubChem)
naphthylaminopropane
Sign in to saveNaphthylaminopropane (NAP; code name PAL-287), also known as naphthylisopropylamine (NIPA), is an experimental drug of the amphetamine and naphthylaminopropane families that was under investigation for the treatment of alcohol and stimulant addiction.
Chemical data
- Formula
- C13H15N
- Molecular weight
- 185.26 g/mol
- IUPAC name
- 1-naphthalen-2-ylpropan-2-amine
- SMILES
- CC(CC1=CC2=CC=CC=C2C=C1)N
- InChIKey
- UPQSZFKXKRKCGZ-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 26 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 185.120449
Show 3 more facts
- chemical formula
- C₁₃H₁₅N
- canonical SMILES
- CC(CC1=CC2=CC=CC=C2C=C1)N
- Commons category
- Naphthylaminopropane
Sources (2)
via Wikidata · CC0
~6 min read
Encyclopedic overview
7 sectionsContents
- Pharmacology
- Pharmacodynamics
- Activities
- Effects
- Chemistry
- See also
- References
Naphthylaminopropane (NAP; code name PAL-287), also known as naphthylisopropylamine (NIPA), is an experimental drug of the amphetamine and naphthylaminopropane families that was under investigation for the treatment of alcohol and stimulant addiction.
==Pharmacology== ===Pharmacodynamics=== ====Activities==== Naphthylaminopropane is a serotonin–norepinephrine–dopamine releasing agent (SNDRA). Its values for induction of monoamine release are 3.4nM for serotonin, 11.1nM for norepinephrine, and 12.6nM for dopamine.
Excerpted from Wikipedia’s “naphthylaminopropane” article, available under the CC BY-SA 4.0 licence.