NCF1
Sign in to saveAlso known as NCF1A, NOXO2, SH3PXD1A, p47phox, Neutrophil cytosolic factor 1, CGD1
protein-coding gene in the species Homo sapiens
Gene data
NCF1- Name
- neutrophil cytosolic factor 1
- Type
- protein-coding
- Position
- 74,773,975–74,789,376 (+)
- Aliases
- CGD1, NCF-1, NCF-47K, NCF1A, NOXO2, SH3PXD1A, p47-phox, p47phox
- Ensembl
- ENSG00000158517
- RefSeq RNA
- NM_000265.7
- RefSeq protein
- NP_000256.4
The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
Chemokine signaling pathway - Homo sapiens (human)Phagosome - Homo sapiens (human)Osteoclast differentiation - Homo sapiens (human)Neutrophil extracellular trap formation - Homo sapiens (human)Fc gamma R-mediated phagocytosis - Homo sapiens (human)Leukocyte transendothelial migration - Homo sapiens (human)Prion disease - Homo sapiens (human)Leishmaniasis - Homo sapiens (human)Diabetic cardiomyopathy - Homo sapiens (human)Lipid and atherosclerosis - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
neutrophil cytosolic factor 1
- Symbol
- NCF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:74,773,975-74,790,135
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein NCF1 PDB 1gd5.png
Show 5 more facts
- HomoloGene ID
- 30964
- exact match
- identifiers.org/ncbigene/653361
- genomic start
- 74774011
- genomic end
- 74789315
- cytogenetic location
- 7q11.23
Sources (4)
via Wikidata · CC0
Connections
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