NELFE

Name

negative elongation factor complex member E

Type

protein-coding

Aliases

D6S45, NELF-E, RD, RDBP, RDP

The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

negative elongation factor complex member E

Symbol

NELFE

Biotype

Protein coding

Organism

Homo sapiens

Location

Chr HSCHR6_MHC_MCF_CTG1:3,294,123-3,301,128

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein RDBP PDB 1x5p.png

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