nifurtimox

Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. In Chagas disease it is a second-line option to benznidazole. It is given by mouth.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 462260534
Drug.image: Nifurtimox.svg
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Drug.width: 250px
Drug.image2: Nifurtimox 3D.png
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Drug.chirality: Racemic mixture
Drug.tradename: Lampit
Drug.DailyMedID: Nifurtimox
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Article

11 sections

Contents

Medical uses
Pregnancy and breastfeeding
Side effects
Contraindications
Mechanism of action
Society and culture
Legal status
Names
Research
References
External links

Common side effects include abdominal pain, headache, nausea, and weight loss. There are concerns from animal studies that it may increase the risk of cancer but these concerns have not been found in human trials. Nifurtimox is not recommended in pregnancy or in those with significant kidney or liver problems. It is a type of nitrofuran.