Structure via PubChem · Public domain (PubChem)
Nitrazepam
Sign in to saveAlso known as Mogadon, Ro-45360, Ro-53059, Sonebon, 2,3-dihydro-7-Nitro-5-phenyl-1H-1,4-benzodiazepin-2-one, 7-Nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one, Paxisyn, Unisomnia
In the Vinony graph
Vinony's link graph records 798 inbound references to Nitrazepam, and connects out to barbiturates, benzodiazepine drug and pharmacokinetics.
Vinony files it under Drugboxes which contain changes to verified fields, Drugboxes which contain changes to watched fields and ECHA InfoCard ID from Wikidata.
Vinony links it to 29 Wikipedia language editions.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 461743504
- Drug.IUPAC_name
- 7-nitro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
- Drug.image
- Nitrazepam.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 222
- Drug.image2
- Nitrazepam-from-xtal-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Alodorm, Apodorm, Arem, Cerson, Insoma, Insomin, Mogadon, Nitrados, Nitrazadon, Nitrosun, Nitravet, Ormodon, Paxadorm, Remnos, Epam, and Somnite
- Drug.dependency_liability
- Physical: High Psychological: Moderate
- Drug.addiction_liability
- Moderate
- Drug.pregnancy_US
- D
- Drug.legal_BR
- B1
- Drug.legal_CA
- Schedule IV
- Drug.legal_AU
- Schedule 4
- Drug.legal_DE
- Rx-only/Anlage III
- Drug.legal_UN
- Psychotropic Schedule IV
via Wikipedia infobox
Chemical data
- Formula
- C15H11N3O3
- Molecular weight
- 281.27 g/mol
- IUPAC name
- 7-nitro-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
- SMILES
- C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3
- InChIKey
- KJONHKAYOJNZEC-UHFFFAOYSA-N
- XLogP
- 2.2
- Polar surface area
- 87.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- epilepsy, anxiety, Dementia, depressive disorder
via ChEMBL · EBI
Research
1,342 papers- Clinical pharmacokinetics of nitrazepam.Clinical pharmacokinetics · 1981
- [Clonazepam, nitrazepam, diazepam].Nihon rinsho. Japanese journal of clinical medicine · 1995
- Nitrazepam (Mogadon) dependence.The British journal of psychiatry : the journal of mental science · 1975
- [Benzodiazepine (clonazepam, nitrazepam, diazepam)].Nihon rinsho. Japanese journal of clinical medicine · 2004
- Nitrazepam nightmares.British medical journal · 1973
via PubMed
Wikidata facts
- Subclass of
- alkaloid
- Mass
- 281.08
- Has use
- medication
Show 7 more facts
- canonical SMILES
- C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3
- World Health Organisation international non-proprietary name
- nitrazepam
- Commons category
- Nitrazepam
- MCN code
- 2933.91.62
- significant drug interaction
- loxapine
- chemical formula
- C₁₅H₁₁N₃O₃
- defined daily dose
- 5
via Wikidata · CC0
Gallery (5)
Connections
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