NPPC

Also known as CNP, CNP2, Natriuretic peptide precursor C, natriuretic peptide C

protein-coding gene in the species Homo sapiens

Gene data

NPPC

Name: natriuretic peptide C
Type: protein-coding
Position: 231,921,809–231,926,396 (−)
Aliases: CNP, CNP2
Ensembl: ENSG00000163273
RefSeq RNA: NM_024409.4, XM_011511245.4, XM_054342295.1
RefSeq protein: NP_077720.1, XP_011509547.1, XP_054198270.1

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015].