Also known as FAM105B, GUM, OTU deubiquitinase with linear linkage specificity, AIPDS
Family with sequence similarity 105, member B is a protein in humans that is encoded by the FAM105B gene.
This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016].
via MyGene.info
Family with sequence similarity 105, member B is a protein in humans that is encoded by the FAM105B gene.
== References ==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).