CALML5
Sign in to saveAlso known as CLSP, calmodulin like 5
Calmodulin-like protein 5 is a protein that in humans is encoded by the CALML5 gene.
Gene data
CALML5- Name
- calmodulin like 5
- Type
- protein-coding
- Position
- 5,498,697–5,499,570 (−)
- Aliases
- CLSP
- Ensembl
- ENSG00000178372
- RefSeq RNA
- NM_017422.5
- RefSeq protein
- NP_059118.2
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
calmodulin like 5
- Symbol
- CALML5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:5,498,697-5,499,570
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CALML5 PDB 2b1u.png
Show 5 more facts
- HomoloGene ID
- 49485
- exact match
- identifiers.org/ncbigene/51806
- genomic end
- 5499570
- genomic start
- 5540658
- cytogenetic location
- 10p15.1
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- External links
- Further reading
Calmodulin-like protein 5 is a protein that in humans is encoded by the CALML5 gene.
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.