ARID5B
Sign in to saveAlso known as DESRT, MRF-2, MRF2, AT-rich interaction domain 5B
AT-rich interactive domain-containing protein 5B is a protein that in humans is encoded by the ARID5B gene.
In the Vinony graph
Within Vinony's link graph, ARID5B is referenced by 4 other articles, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 10.
Its subject is documented across 6 Wikipedia language editions.
Gene data
ARID5B- Name
- AT-rich interaction domain 5B
- Type
- protein-coding
- Position
- 61,901,246–62,096,944 (+)
- Aliases
- DESRT, MRF-2, MRF2
- Ensembl
- ENSG00000150347
- RefSeq RNA
- NM_001244638.2, NM_032199.3
- RefSeq protein
- NP_001231567.1, NP_115575.1
This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
AT-rich interaction domain 5B
- Symbol
- ARID5B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:61,901,246-62,096,944
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ARID5B PDB 1ig6.png
Show 8 more facts
- HomoloGene ID
- 45872
- chromosome
- human chromosome 10
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/84159
- genomic end
- 63856703
- genomic start
- 61901684
- cytogenetic location
- 10q21.2
- expressed in
- superficial temporal artery
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Genomics
- Clinical importance
- References
- External links
- Further reading
AT-rich interactive domain-containing protein 5B is a protein that in humans is encoded by the ARID5B gene.
Alternative names for this gene include Modulator recognition factor 23.
Excerpted from Wikipedia’s “ARID5B” article, available under the CC BY-SA 4.0 licence.