annexin

Also known as IPR001464, Annexins

Annexin is a common name for a group of cellular proteins. They are mostly found in eukaryotic organisms (animals, plants and fungi).

Key facts

Protein family.Symbol: Annexin
Protein family.Name: Annexin
Protein family.image: Annexin.png
Protein family.width: 220
Protein family.caption: Structure of human annexin III.
Protein family.Pfam: PF00191
Protein family.InterPro: IPR001464
Protein family.PROSITE: PDOC00195
Protein family.SCOP: 2ran
Protein family.TCDB: 1.A.31
Protein family.OPM family: 41
Protein family.OPM protein: 1w3w

via Wikipedia infobox

Research

35,104 papers

Annexin A11 aggregation in FTLD-TDP type C and related neurodegenerative disease proteinopathies.Acta neuropathologica · 2024
Annexin-actin interactions.Traffic (Copenhagen, Denmark) · 2004
Annexin A1, A2, A5, and A6 involvement in human pathologies.Proteins · 2023
Annexin A family: A new perspective on the regulation of bone metabolism.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
The role of the annexin A protein family at the maternal-fetal interface.Frontiers in endocrinology · 2024

via PubMed

~15 min read

Encyclopedic overview

20 sections

Contents

Introduction
Structure
Cellular localization
Membrane
Nuclei
Bone
Role in vesicle transport
Exocytosis
Endocytosis
Membrane scaffolding
Membrane organization and trafficking
Clinical significance
Apoptosis and inflammation
Coagulation
Fibrinolysis
Types/subfamilies
Human proteins containing this domain
References
Further reading
External links

Annexin is a common name for a group of cellular proteins. They are mostly found in eukaryotic organisms (animals, plants and fungi).

In humans, the annexins are found inside the cell. However some annexins (Annexin A1, Annexin A2, and Annexin A5) can be secreted from the cytoplasm to outside cellular environments, such as blood.

Excerpted from Wikipedia’s “annexin” article, available under the CC BY-SA 4.0 licence.

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