ANXA5

Name

annexin A5

Type

protein-coding

Position

121,667,396–121,697,061 (−)

Aliases

ANX5, CPB-I, ENX2, HEL-S-7, PP4, RPRGL3, VAC-alph

Ensembl

ENSG00000164111

RefSeq RNA

NM_001154.4, XM_017008141.3, XM_054349860.1

RefSeq protein

NP_001145.1, XP_016863630.1, XP_054205835.1

The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications. [provided by RefSeq, Dec 2019].

via MyGene.info

Gene · Ensembl

annexin A5

Symbol

ANXA5

Biotype

Protein coding

Organism

Homo sapiens

Location

4:121,644,102-121,697,330

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein ANXA5 PDB 1a8a.png

via Wikidata · CC0