ANXA2
Sign in to saveAlso known as ANX2, ANX2L4, CAL1H, HEL-S-270, LIP2, LPC2, LPC2D, P36
protein-coding gene in the species Homo sapiens
Gene data
ANXA2- Name
- annexin A2
- Type
- protein-coding
- Aliases
- ANX2, ANX2L4, CAL1H, HEL-S-270, LIP2, LPC2, LPC2D, P36, PAP-IV
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019].
via MyGene.info
Gene · Ensembl
annexin A2
- Symbol
- ANXA2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:60,347,134-60,402,883
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein ANXA2 PDB 1w7b.png
Show 5 more facts
- HomoloGene ID
- 20857
- exact match
- identifiers.org/ncbigene/302
- genomic start
- 60639333
- genomic end
- 60695082
- cytogenetic location
- 15q22.2
via Wikidata · CC0