DOK5
Sign in to saveAlso known as C20orf180, IRS-6, IRS6, docking protein 5
Docking protein 5 is a protein that in humans is encoded by the DOK5 gene.
Gene data
DOK5- Name
- docking protein 5
- Type
- protein-coding
- Aliases
- C20orf180, IRS-6, IRS6
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014].
via MyGene.info
Gene · Ensembl
docking protein 5
- Symbol
- DOK5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:54,475,459-54,651,171
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein DOK5 PDB 1j0w.png
Show 5 more facts
- HomoloGene ID
- 10195
- exact match
- identifiers.org/ncbigene/55816
- genomic end
- 54651169
- genomic start
- 54475593
- cytogenetic location
- 20q13.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Docking protein 5 is a protein that in humans is encoded by the DOK5 gene.
== Function ==