SMG5

Also known as EST1B, LPTS-RP1, LPTSRP1, SMG-5, SMG5, nonsense mediated mRNA decay factor, SMG5 nonsense mediated mRNA decay factor

Protein SMG5 is a protein that in humans is encoded by the SMG5 gene. This protein contains a PIN domain that appears to have mutated the residues in the active site.

In the Vinony graph

Vinony's link graph records 6 inbound references to SMG5, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 1.

Vinony links it to 8 Wikipedia language editions.

Gene data

SMG5

Name: SMG5 nonsense mediated mRNA decay factor
Type: protein-coding
Position: 156,249,223–156,282,862 (−)
Aliases: EST1B, LPTS-RP1, LPTSRP1, SMG-5
Ensembl: ENSG00000198952
RefSeq RNA: NM_001323614.2, NM_001323615.2, NM_001323616.2, NM_001323617.2, NM_015327.3
RefSeq protein: NP_001310543.1, NP_001310544.1, NP_001310545.1, NP_001310546.1, NP_056142.2

SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM, Mar 2008].

Pathways

mRNA surveillance pathway - Homo sapiens (human)Metabolism of RNA Nonsense-Mediated Decay (NMD)Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

via MyGene.info

Gene · Ensembl

SMG5 nonsense mediated mRNA decay factor

Symbol: SMG5
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:156,249,223-156,282,862
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein SMG5 PDB 2hwy.png

Show 7 more facts

HomoloGene ID: 9095
genomic end: 156282825
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/23381
genomic start: 156219015
chromosome: human chromosome 1
cytogenetic location: 1q22

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Protein SMG5 is a protein that in humans is encoded by the SMG5 gene. This protein contains a PIN domain that appears to have mutated the residues in the active site.

==References==

Excerpted from Wikipedia’s “SMG5” article, available under the CC BY-SA 4.0 licence.